Exercise testing in patients with asymptomatic systolic heart failure

The project will further investigate two factors related to exercise capacity in NYHA I patients: the influence of the right heart and quality of life/mental health.

First, general exercise capacity will be assessed by spiroergometry (maximal oxygen uptake, respiratory efficiency, oxygen pulse, etc.). The scientists will investigate potential abnormalities between the reported NYHA class and the recorded physical exercise capacity. In a second step, the potential influencing factors are analyzed. Right ventricular pump function and inferior vena cava respiratory variability will be worked up using echocardiographic data and assessed as possible determinants of better or worse endurance capacity. Questionnaires on quality of life, mental health, and personality factors will be analyzed with respect to exercise capacity. In the project, an analysis will be performed affiliated to the multicenter cohort study Transition CHF-DZHK2 (congestive heart failure) of the DZHK. The aim is to collect data from NYHA I patients to build a biobank of this underrepresented cohort.

Publications

There are no publications available yet.

Project Term
11/2022 - 11/2023
Research resource used
Resource liquid samples/image data
Keywords
NYHA 1, spiroergometry, right heart function, quality of life